Vaccination in Pregnancy: What Is Safe for Mother and Baby

Vaccination during pregnancy is an important part of protecting both the mother and baby from certain serious infections.

Some vaccines are recommended during pregnancy, while others should be avoided until after delivery. The right vaccination plan depends on the mother’s health, previous vaccination history, pregnancy stage, and risk of infection.

Why Vaccination Is Important During Pregnancy

Pregnancy changes the immune system and can make some infections more serious.

Vaccines can help:

  • Protect the mother from serious infections.
  • Reduce the risk of complications during pregnancy.
  • Help protect the baby before birth.
  • Pass protective antibodies from the mother to the baby.
  • Give the baby some early protection during the first months after birth.

Vaccines Commonly Recommended During Pregnancy

1. Tdap Vaccine

The Tdap vaccine protects against:

  • Tetanus
  • Diphtheria
  • Pertussis, also called whooping cough

Tdap is recommended during each pregnancy, usually between 27 and 36 weeks.

The mother develops antibodies after vaccination. Some of these antibodies cross the placenta and help protect the baby against whooping cough during the early period after birth.

2. Influenza Vaccine

Pregnant women can have a higher risk of serious complications from influenza.

The injectable inactivated flu vaccine can be given during pregnancy, including during any trimester when indicated.

It can help:

  • Reduce the mother’s risk of serious flu illness.
  • Reduce the risk of flu-related complications.
  • Provide antibodies that can help protect the baby after birth.

The nasal-spray live influenza vaccine is not recommended during pregnancy.

3. COVID-19 Vaccine
  • COVID-19 infection can cause more serious illness during pregnancy.
  • Current WHO guidance supports COVID-19 vaccination during pregnancy, while recommendations can vary by country and individual circumstances.
  • Vaccination can help reduce the risk of severe COVID-19 illness, and antibodies can also provide some protection to the baby.

Vaccines Usually Avoided During Pregnancy

Some vaccines are generally not given during pregnancy because they contain live, weakened forms of viruses.

These include:

  • MMR vaccine
  • Varicella or chickenpox vaccine
  • Live nasal influenza vaccine
  • HPV vaccine during pregnancy

These vaccines may be recommended before pregnancy or after delivery depending on the mother’s vaccination history and medical needs.

Vaccines Needed Before Pregnancy

Planning vaccination before pregnancy can help provide protection from infections that may be harmful during pregnancy.

Before trying to conceive, discuss:

  • Previous vaccination records.
  • MMR vaccination status.
  • Chickenpox vaccination status.
  • Influenza vaccination.
  • Hepatitis vaccination when indicated.
  • Other vaccines based on travel, medical history, and infection risk.

This planning can help avoid delays in protection during pregnancy.

Vaccination and Breastfeeding

  • Many routine vaccines can be given after delivery, including while breastfeeding.
  • Breastfeeding mothers should still discuss vaccination with their healthcare provider, especially when considering travel-related or special vaccines.

Mild Side Effects Can Occur

Some vaccines may cause temporary side effects such as:

  • Pain or soreness at the injection site.
  • Mild swelling or redness.
  • Tiredness.
  • Headache.
  • Mild fever.
  • Muscle aches.

These effects are generally short-lasting. Severe reactions are uncommon, but any unusual or serious symptoms should be discussed with a healthcare professional.

Keep Your Vaccination Records Updated

Pregnant women should keep their vaccination records available during antenatal visits.

Doctors may consider:

  • Previous vaccines received.
  • Current pregnancy stage.
  • Medical conditions.
  • Previous allergic reactions.
  • Travel plans.
  • Exposure to particular infections.
  • Local vaccination recommendations.

At Motherly Hospitals, the vaccination plan can be discussed as part of regular pregnancy care so that mothers understand which vaccines may be appropriate for their individual situation.

Do Not Take Vaccines Without Medical Advice

Not every vaccine is suitable for every pregnant woman.

Before receiving a vaccine:

  • Inform your doctor that you are pregnant.
  • Share your previous vaccination records.
  • Mention any serious allergies.
  • Tell your doctor about existing medical conditions.
  • Discuss recent vaccines